@font-face{font-family:Manrope;src:url('./manrope-variable.woff2') format('woff2');font-weight:200 800;font-style:normal;font-display:swap}
:root{--bg:#f3f5f2;--surface:#fff;--ink:#202e29;--muted:#56645d;--green:#155b40;--pale:#e6efe8;--line:#dbe2dc;--control:#74867a;--radius:24px;--inset:5px;--ease:cubic-bezier(.22,.68,0,1)}
*{box-sizing:border-box}body{margin:0;background:var(--bg);color:var(--ink);font: .875rem/1.55 Manrope,system-ui,sans-serif}button,input,select{font:inherit}button,a,summary,input,select{-webkit-tap-highlight-color:transparent}button,select,input{min-height:44px;border:1px solid var(--control);border-radius:12px;background:#fff;color:var(--ink);padding:10px 14px;max-width:100%;min-width:0}button{cursor:pointer;white-space:nowrap;flex-shrink:0;font-weight:650;transition:background-color 160ms var(--ease),transform 160ms var(--ease)}button:hover{background:var(--pale)}button:active{transform:scale(.98)}button:disabled{cursor:wait;color:var(--muted)}button.primary{background:var(--green);border-color:var(--green);color:white;padding-inline:24px}button.primary:hover{background:#124b35}label{display:flex;flex-direction:column;gap:6px;font-size:.75rem;font-weight:650;min-width:0}select{appearance:none;padding-right:38px;background-image:linear-gradient(45deg,transparent 50%,var(--ink) 50%),linear-gradient(135deg,var(--ink) 50%,transparent 50%);background-position:calc(100% - 18px) 19px,calc(100% - 13px) 19px;background-size:5px 5px;background-repeat:no-repeat}input[type=date]{width:100%}input::placeholder{color:var(--muted)}[hidden]{display:none!important}:focus-visible{outline:3px solid var(--green);outline-offset:3px;transition:none!important}.skip{position:absolute;left:16px;top:-100px;background:#fff;padding:12px;z-index:3}.skip:focus{top:16px}.app-shell{display:grid;grid-template-columns:228px minmax(0,1fr);max-width:1800px;margin:auto;min-height:100dvh}.sidebar{margin:24px 0 24px 24px;padding:24px 16px;position:sticky;top:24px;height:calc(100dvh - 48px);background:#eaf0e9;border-radius:24px;display:flex;flex-direction:column;gap:40px}.brand{display:flex;align-items:center;gap:10px;padding:0 10px;font-weight:800;letter-spacing:.035em}.brand svg{width:32px;height:32px;fill:var(--green);flex:none}.brand small{display:block;color:var(--muted);font-size:.6875rem;font-weight:500;letter-spacing:0;margin-top:2px}nav{display:flex;flex-direction:column;gap:8px}nav a{min-height:48px;display:flex;align-items:center;gap:12px;padding:12px 14px;text-decoration:none;color:var(--muted);border-radius:14px;font-weight:600}nav a svg{width:20px;height:20px;stroke:currentColor;stroke-width:1.4;fill:none;flex:none}nav a:hover{background:#dde9df}nav a[aria-current=page]{color:#fff;background:var(--green);box-shadow:0 6px 18px #155b4012}nav a[aria-current=page]::after{content:'';margin-left:auto;flex:none;width:5px;height:5px;border-radius:50%;background:#fff}.sidebar-foot{margin-top:auto;padding:10px;display:flex;flex-direction:column;gap:12px;font-size:.75rem}.sidebar-foot p{margin:0}.sidebar-foot small{display:block;color:var(--muted)}.sidebar-foot button{background:transparent}.sidebar-foot #actor{color:var(--muted)}main{padding:36px 36px 24px;min-width:0}.page-heading{display:flex;align-items:center;justify-content:space-between;gap:20px;margin-bottom:24px}h1,h2,h3,p{margin-top:0}h1{font-size:1.75rem;letter-spacing:-.04em;line-height:1.2;margin-bottom:8px;font-weight:750}h2,h3{font-size:1.125rem;line-height:1.4;letter-spacing:-.02em;margin-bottom:12px}#view-description{color:var(--muted);margin:0}.eyebrow{font-size:.625rem;text-transform:uppercase;letter-spacing:.17em;font-weight:700;color:var(--muted);margin-bottom:8px}.badge{background:var(--pale);padding:8px 12px;border-radius:99px;color:var(--green);font-size:.6875rem;font-weight:700;white-space:nowrap}.toolbar{padding:16px 20px;border-radius:20px;background:#e9eeea;margin-bottom:24px}.toolbar-row{display:flex;gap:12px;align-items:end;flex-wrap:wrap}.toolbar-row label{min-width:120px;flex:0 1 auto}.toolbar-row+.toolbar-row{margin-top:12px}.toolbar .hint{margin:10px 0 0}.toolbar #filter-error:empty{display:none}#filter-error{color:#973c23;margin:12px 0 0}#advanced-filters{margin-top:8px}details>summary{cursor:pointer;min-height:44px;align-content:center;font-weight:650;color:var(--green);padding:8px 0}details[open]>summary{margin-bottom:8px}.catalog{border:0;padding:12px 0 0;margin:0}.catalog legend{font-size:.75rem;color:var(--muted)}.catalog-grid{display:grid;grid-template-columns:1fr 1fr;gap:24px}.catalog-grid>div{display:grid;grid-template-columns:minmax(0,1fr) auto;gap:12px;align-items:end}.catalog-grid label{grid-column:1}.catalog-grid p{grid-column:1/-1}.hint,.formula,.meta,small{color:var(--muted)}.hint,.formula{font-size:.75rem;line-height:1.65;margin-bottom:12px}.meta{font-size:.6875rem;border-top:1px solid var(--line);padding-top:12px;margin:16px 0 0}.panel{min-width:0;background:#e5eae5;padding:var(--inset);border-radius:var(--radius);box-shadow:0 14px 40px #293c2908;margin-bottom:20px}.panel-core{min-width:0;background:var(--surface);padding:24px;border-radius:calc(var(--radius) - var(--inset));box-shadow:inset 0 1px 0 #ffffff80}.bento{display:grid;grid-template-columns:minmax(0,1.9fr) minmax(260px,1fr);gap:20px}.bento .panel{margin-bottom:20px}.primary-panel{min-width:0}.panel-heading{display:flex;gap:20px;justify-content:space-between;align-items:center;margin-bottom:16px}.panel-heading h2{margin:0}.cards{display:grid;grid-template-columns:1.35fr 1fr 1fr 1fr;gap:16px;margin-bottom:20px}.metric{background:#fff;box-shadow:0 10px 32px #293c2906;border:5px solid #e5eae5;border-radius:24px;padding:20px 16px;min-width:0}.metric:first-child{background:var(--green);border-color:#d7e5da;color:#fff}.metric p{font-size:.75rem;font-weight:650;margin:0 0 12px}.metric strong{display:block;font-size:clamp(1.4rem,2vw,2rem);letter-spacing:-.05em;line-height:1.25;overflow-wrap:anywhere;font-variant-numeric:tabular-nums;margin-bottom:12px}.metric small{display:block;font-size:.6875rem;line-height:1.6;margin-top:4px}.metric:first-child small{color:#dcebe1}#panel-overview>details,#panel-overview>.formula,#panel-overview>.meta{margin-left:8px;margin-right:8px}#panel-overview>details{margin-bottom:20px}.chart{width:100%;height:auto;display:block;aspect-ratio:700/280;min-height:180px;max-height:340px}.chart text{font-family:Manrope,system-ui,sans-serif;font-size:12px;fill:var(--muted)}.chart-bar{fill:var(--green)}.chart-grid{stroke:var(--line);stroke-width:1}.chart .missing-mark{fill:#973c23}.chart-title{font-size:.875rem;font-weight:700;margin:20px 0 8px}.chart-block{margin-bottom:24px}.chart-block>details{background:#f5f7f4;border-radius:12px;padding:0 12px}.table-wrap{max-width:100%;overflow:auto;border-radius:12px;margin:12px 0}table{width:100%;border-collapse:collapse;text-align:left;font-size:.75rem}caption{text-align:left;font-weight:700;margin-bottom:12px;color:var(--ink)}th,td{padding:12px 14px;vertical-align:top;border-bottom:1px solid var(--line)}thead{background:#f0f4ef;color:var(--muted)}tbody th{font-weight:600}td{font-variant-numeric:tabular-nums}tbody tr:last-child>*{border-bottom:0}.empty,.notice{background:#eef3ed;padding:20px;border-radius:16px;color:var(--muted)}.text-link{display:inline-flex;align-items:center;min-height:44px;color:var(--green);font-weight:700;text-decoration:underline;font-size:.75rem}.mini-stat{padding:16px 0;border-bottom:1px solid var(--line)}.mini-stat strong{display:block;font-size:1.75rem;letter-spacing:-.04em;color:var(--ink)}.mini-stat small{display:block;font-size:.75rem}.trial-grid{display:grid;grid-template-columns:1fr 1fr;gap:20px;margin:20px 0}.cohort{background:#f1f5ef;padding:20px;border-radius:16px}.cohort h3{font-size:.875rem}.cohort strong{display:block;font-size:2rem;letter-spacing:-.04em;color:var(--green)}.cohort dl{display:grid;grid-template-columns:1fr auto;gap:8px;margin-bottom:0;font-size:.75rem}.cohort dd{margin:0;font-weight:700}.problem-group{margin:20px 0;padding:20px;background:#f5f7f4;border-radius:16px}.problem-group h3{font-size:1rem}.pagination{display:flex;flex-wrap:wrap;align-items:center;gap:12px;font-size:.75rem}.access-total{font-size:2rem;color:var(--green);font-weight:750;letter-spacing:-.04em;margin-bottom:8px}footer{font-size:.6875rem;color:var(--muted);padding:12px 8px}footer p{margin:0}
@media(min-width:1600px){main{padding-inline:48px}.cards{gap:20px}}
@media(max-width:1100px){.app-shell{grid-template-columns:196px minmax(0,1fr)}.sidebar{margin-left:16px;padding-inline:10px}main{padding:32px 24px}.cards{grid-template-columns:1fr 1fr}.bento{grid-template-columns:1fr}.catalog-grid{grid-template-columns:1fr}.panel-heading{align-items:start;flex-direction:column}}
@media(max-width:767px){.app-shell{display:block}.sidebar{position:static;height:auto;margin:16px;padding:16px;gap:16px}.brand{padding:0}.sidebar nav{display:grid;grid-template-columns:repeat(3,minmax(0,1fr));gap:8px}.sidebar nav a{padding:10px 8px;justify-content:center;gap:6px;font-size:.6875rem;min-height:44px}.sidebar nav a svg{width:16px;height:16px}.sidebar nav a::after{display:none}.sidebar-foot{margin:0;padding:0;flex-direction:row;align-items:center;flex-wrap:wrap;gap:12px}.sidebar-foot p{margin-right:auto}.sidebar-foot button{padding:8px 14px}.sidebar-foot #actor{display:none}main{padding:12px 16px 24px}.page-heading{margin-bottom:20px;gap:12px}.page-heading .badge{display:none}h1{font-size:1.625rem}.toolbar{padding:16px}.toolbar-row{gap:12px}.toolbar-row label{flex:1 1 100px;min-width:0}.toolbar-row button{flex:1}.catalog-grid>div{grid-template-columns:1fr}.catalog-grid label{grid-column:auto}.panel-core{padding:20px 16px}.cards{gap:12px}.metric{padding:16px 12px;border-width:4px;border-radius:20px}.metric strong{font-size:1.5rem}.metric p{font-size:.6875rem}.metric small{font-size:.625rem}.trial-grid{grid-template-columns:1fr}.panel-heading{gap:16px}.panel-heading>.toolbar-row{width:100%}.chart{min-height:160px}.bento{gap:0}.table-wrap{margin-inline:0}.sidebar nav a{flex-direction:column;gap:2px}.sidebar nav a svg{height:18px}.problem-group{padding:16px}.page-heading p{font-size:.75rem}}
@media(max-width:359px){.cards{grid-template-columns:1fr}.metric strong{font-size:1.625rem}.sidebar{margin:12px}main{padding-inline:12px}.toolbar{padding:12px}.sidebar nav a{font-size:.625rem}.chart{min-height:140px}}
@media(prefers-reduced-motion:reduce){*,*::before,*::after{animation:none!important;transition:none!important;scroll-behavior:auto!important}}

.bento>.panel{align-self:start}.metric small{overflow-wrap:anywhere}.quality-note{padding:10px 12px;background:#f4eedf;color:#69521b;border-radius:10px;font-size:.75rem}

#panel-overview>.quality-note{margin:0 8px 4px;padding:6px 10px}#panel-overview>details{margin-bottom:12px}.metric{padding-top:16px;padding-bottom:16px}.metric strong{margin-bottom:8px}.toolbar{margin-bottom:20px}.toolbar #advanced-filters{margin-top:0}.toolbar #active-filters{margin-top:6px}#panel-overview>details>summary{font-size:.75rem}

@media(max-width:767px){.toolbar>.toolbar-row{display:grid;grid-template-columns:minmax(0,1fr) minmax(0,1fr);align-items:end}.toolbar>.toolbar-row button{min-width:fit-content;flex-shrink:0;width:100%}.sidebar{position:relative;gap:12px}.brand{min-height:44px;padding-right:76px}.sidebar-foot{position:absolute;top:16px;right:16px}.sidebar-foot p{display:none}.sidebar-foot button{background:#fff}.page-heading .eyebrow{display:none}.page-heading{margin-bottom:16px}.sidebar nav a{min-height:44px}.sidebar{margin-bottom:12px}.toolbar{margin-bottom:16px}.page-heading h1{margin-bottom:4px}}

main{padding-top:24px}.page-heading{margin-bottom:20px}.toolbar{padding-top:12px;padding-bottom:12px;margin-bottom:16px}.metric p{margin-bottom:8px}.metric strong{line-height:1.15}.cards{margin-bottom:12px}.panel-core>.hint{margin-bottom:8px}.chart-block:first-child>.chart-title{margin-top:0}

.chart{aspect-ratio:auto;height:280px;min-height:280px;max-height:280px}
/* Readable product copy keeps its size when the layout gets narrower. */
body{font-size:1rem}button,input,select{font-size:1rem;min-height:48px}label{font-size:.875rem}nav a{font-size:1rem}.hint,.formula,.quality-note,.pagination,table,.text-link{font-size:.875rem}.metric p,.metric small,.mini-stat small,.cohort dl,.sidebar-foot,.sidebar-foot small{font-size:.875rem}.metric small{line-height:1.5}.metric p{line-height:1.5}.meta,footer{font-size:.75rem}.chart text{font-size:12px}.catalog legend{font-size:.875rem}#panel-overview>details>summary{font-size:.875rem}.cohort h3{font-size:1rem}
@media(max-width:767px){.sidebar nav a{font-size:.875rem;padding:8px 4px}.page-heading p{font-size:.875rem}.metric p,.metric small{font-size:.875rem}.metric strong{font-size:1.5rem}.sidebar-foot button{padding:8px 14px}.toolbar>.toolbar-row button{padding-inline:12px}.metric{padding:16px 12px}.brand small{font-size:.75rem}}
@media(max-width:449px){.sidebar nav{grid-template-columns:repeat(2,minmax(0,1fr))}.sidebar nav a{flex-direction:row;gap:8px}.sidebar nav a svg{width:18px;height:18px}.sidebar{gap:12px}.sidebar nav a{font-size:.875rem;justify-content:start;padding:10px 12px}}

.chart-title{font-size:1rem}
footer{font-size:.875rem}